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Management of Anticoagulant and While only 1 drug, recombinant tissue-type plasminogen activator (alteplase or generiy referred to as rt-PA), has demonstrated efficacy and effectiveness in treating acute ischemic stroke and is approved by the FDA, other medications are equally important. Antiplatelet-Related ICH. Antiplatelet medication has been shown to be a risk factor for spontaneous ICH as well as increased ICH volume and increased mortality, but.
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